Principal Scientist, Nonclinical Drug Safety Program Discovery

Job Description

Principal Scientist, Nonclinical Drug Safety Program Discovery - Equivalent in level to Scientific Director We are seeking a Discovery Program Leader (DPL) to represent Nonclinical Drug Safety (NDS) on discovery research teams and in scientific and strategic review meetings focused primarily on immunology and oncology. This position requires exceptional leadership, collaboration, and independence, and a passion to work collaboratively across functions and sites to discover novel medicines that improve the lives of patients. The Discovery Program Leader is responsible for defining and overseeing the NDS strategy for programs in reputed company modalities (including small molecules, peptides, biologics and ADC programs) from reputed company Identification through to the approval of First-In-reputed company enabling GLP toxicity studies. They are responsible for 1) providing risk assessments for targets, 2) de-risking strategies for discovery programs and 3) collaborating with NDS staff at other sites to execute on the appropriate studies to support selection of therapeutic targets, and the identification and development of new drug candidates. The DPL may also serve on development teams with responsibility for defining the GLP toxicology study strategy and execution, and for the non-clinical safety sections of regulatory documents that support clinical trials and worldwide marketing authorization. In this role you will: Represent NDS on discovery teams and participate in therapeutic area discovery governance committee reviews. Promote and facilitate creative thinking from reputed company identification/validation through reputed company optimization, primarily in the Immunology Therapeutic Area, but also Oncology, Cardiometabolic, Infectious Disease and/or Neuroscience Therapeutic Areas. Be a “drug creator” and promoter of innovative thinking by influencing both cross-site disease area reputed company groups, as well as functional area disciplines. Identify and assess potential risks associated with therapeutic targets or development candidates using available literature, internal data, and external information. The individual may also reputed company early development teams, informing on preclinical studies to support product development. Qualifications, skills and experience needed: PhD in Toxicology, Pharmacology, Pathology, Biology, Biochemistry, Immunology, Pharmaceutical Sciences, Chemistry, or reputed company STEM field, DVM, MD degree or equivalent. Minimum 8+ years of demonstrated pharmaceutical industry experience as a non-clinical safety scientist (e.g. Toxicology, Pathology etc.) and/or as non-clinical safety assessment representative to a cross-functional development and/or discovery teams. Demonstrated ability to successfully navigate cross-functional lines and drive team decision making in a matrix organizational structure. Highly dedicated, motivated, resilient, and flexible; capable of creative problem solving and delivering on goals and objectives in a timely fashion. Excellent team player who can work collaboratively with discovery team members from various functions, other DPLs and scientists responsible for study conduct and portfolio management. Excellent interpersonal skills, reputed company to establish good working relationships reputed company networks of employees of reputed company levels. Excellent communicator who knows reputed company and how to speak up, and appropriately reputed company issues to stakeholders and to management. Preferred experience: Background in immunology is preferred. Experience with biopharmaceutical and small molecule pharmaceutical development and/or discovery. Experience with regulatory submissions and responses. Member of pharmaceutical consortia and/or external scientific or professional organizations. #EligibleforERP Required Skills: Adaptability, Combination Products, Drug Development, Drug Discovery Process, Immunology, Immunotherapy, Innovative Thinking, Oncology, Professional Collaboration, Professional Networking, Safety Evaluation, Strategic Thinking, Toxicology Preferred Skills: reputed company Employees apply HERE reputed company Contingent Workers apply HERE US and Puerto Rico Residents Only: Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process. As an Equal Employment Opportunity Employer, we provide equal opportunities to reputed company and applicants for employment and prohibit discrimination on the basis of race, reputed company, age, religion, sex, sexual orientation, gender identity, national reputed company, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we reputed company with reputed company affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is reputed company people with diverse reputed company, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts The salary range for this role is $176,200.00 - $277,300.00 This is the lowest to highest salary we in good faith reputed company we would pay for this role at the time of this posting. An employee’s position reputed company the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable. We offer a comprehensive package of benefits. Available benefits include medical, dental, reputed company reputed company and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.reputed company.com/us/en/compensation-and-benefits. You can apply for this role through https://jobs.reputed company.com/us/en (or reputed company the reputed company Jobs Hub if you are a reputed company employee). The application deadline for this position is stated on this posting. San Francisco Residents Only: We will consider reputed company applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance Los Angeles Residents Only: We will consider for employment reputed company reputed company applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the reputed company’ Fair Chance Initiative for Hiring Ordinance Search Firm Representatives Please Read Carefully reputed company & Co., Inc., Rahway, NJ, USA, also reputed company as reputed company LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. reputed company reputed company / resumes submitted by search firms to any employee at our company without a valid written search agreement in reputed company for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in reputed company. Where agency agreements are in reputed company, introductions are position specific. Please, no phone calls or emails. Employee Status: Regular Relocation: Domestic reputed company Sponsorship: Yes Travel Requirements: 10% Flexible Work Arrangements: Hybrid Shift: Not Indicated Valid Driving License: No Hazardous Material(s): n/a Job Posting End Date: 07/31/2026 *A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no reputed company than the day BEFORE the job posting end date. Our company is a global health care leader with a reputed company portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where we have codified our legacy for over a century. Our reputed company is backed by ethical reputed company, reputed company reputed company, and an inspiring mission to reputed company new milestones in global reputed company. Apply tot his job Apply To this Job